West Virginia College of Law professor S. Sean Tu recently published new scholarship in the Journal of Law and the Biosciences. The article is titled "Accelerating biosimilar market access: the case for allowing earlier standing". Professor Tu's co-authors are: Rachel Goode and Matthew Turner of Fresenius Kabi Biopharma, and Victor Van de Wiele, Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women’s Hospital. The article was published online by the journal on January 3, 2025 and subsequently in print in volume 12, issue 1 of the journal.
From the abstract:
Biosimilars, which are affordable alternatives to biologic medicines, face delays in market entry due to the current patent litigation framework under the Biologic Price Competition and Innovation Act. Currently, biosimilar manufacturers can only initiate patent litigation to attempt to clear weak and invalid patents after submitting their Biologic License Application to the Food and Drug Administration (FDA), which happens after completing extensive, and costly clinical trials. By contrast, generic drug manufacturers can start litigation earlier due to shorter development times and less stringent clinical requirements, allowing them to launch immediately after the primary patent expires. We propose allowing biosimilars to begin patent litigation at the start of phase 3 clinical trials, the final stage of biosimilar development, where the product and manufacturing process and product profile are largely finalized. This change would enable biosimilar firms to resolve patent issues well before the brand biologic’s primary patent expiration date, potentially reducing market entry delays by about 1.8 years. This article examines the issues surrounding initiation of biosimilar litigation and suggests litigation reforms to expedite biosimilar market availability..
Find more of Professor Tu's scholarship on SSRN.